Abstract | Mangroves are the evergreen salt-tolerant trees and shrubs growing in sheltered tidal waters between mean low water of neap tides and extremely high water of spring tides on tropical shores and sub-tropical regions. The extraction of natural chemical compounds from the mangrove trees and other substances of interest to modern industry and medicine are of great significance today. Endophytic fungi have a biotechnological potential and are a valuable source of useful metabolites. The aim of this proposed study will be to investigate the endophytic fungi diversity on selected healthy mangrove plants in the three creeks (Mida, Gazi, and Tudor) along the Kenyan coast from which bioactive compounds may be extracted, purified, characterized, and analyzed for antimicrobial properties against common human pathogens (Staphylococcus aureus, Escherichia coli, Candida albicans). The findings of this study will ascertain their potential for application in the pharmaceutical industry. |